CKD and Novel Biomarkers

Session Description:
Renal disease is the functional loss of kidneys that is represented by tissue pathology and changes in the expression of circulating molecules found in plasma and urine. These molecules can be biomarkers of present and future organ loss. In addition, some may also act as drivers (biomarkers) and therefore are directly involved in causing chronic kidney disease and disturbances of the cardiovascular system. This session will discuss key biomarker and biomarkers of chronic kidney disease, explore how large data sets aid in the diagnosis, evaluation and treatment of kidney disease and provide new mechanistic and epidemiologic insights into the dysregulated cardio-renal axis seen in chronic kidney disease. Some of the discussed molecules may inform future drug trials or have become drug targets themselves.

Learning Objectives:
Understanding the landscape of biomarkers and biomarkers in chronic kidney disease. Appreciating the value of large datasets gleaned from patients with chronic kidney disease and mining of new drug targets. Discussing the mechanistic underpinnings of a disturbed cardio-renal axis in chronic kidney disease.